They appear intended to send a message that Russia, despite the costly five-month war in Ukraine, remains focused on the defence of its entire territory and capable in military terms of sustaining "business as usual".
But that may be a challenge given Russia's heavy losses in men and equipment in Ukraine - including troops and hardware sent there from the eastern military district where the war games will take place.
"A lot of troops and gear from the eastern MD (military district) have already been deployed, rotated, lost and killed in Ukraine since February so this will be interesting to see what they can salvage," said Mathieu Boulegue, a military specialist at London's Chatham House think-tank.
In a statement, the defence ministry emphasised that its capacity to stage such drills was unaffected by what it calls its "special military operation" in Ukraine.
It said Russia had not cancelled any training activities or international co-operation, and the exercises would be supplied with all necessary personnel, weapons and equipment.
"We draw your attention to the fact that only a part of the Armed Forces of the Russian Federation is involved in the special military operation (in Ukraine), the number of which is quite sufficient to fulfil all the tasks set by the Supreme Commander-in-Chief," the statement said.
CIA Director William Burns said last week the United States estimated that 15,000 Russian troops had been killed in Ukraine since February - as many deaths as the Soviet army sustained in a decade of war in Afghanistan from 1979 - and three times that many may have been wounded.
The eastern military district includes part of Siberia and has its headquarters in Khabarovsk, near the Chinese border.
The exercises will include some foreign forces, the defence ministry said, without specifying from which countries.
The previous Vostok drills in 2018 took place on a massive scale with nearly 300,000 troops reported to be involved, including for the first time from the Chinese army.
Russian authorities also said on Tuesday that its forces killed several dozen foreign fighters in an attack on a Ukrainian Foreign Legion unit near Kostyantynivka in Donetsk, noting that most of those who died were Polish.
The Foreign Legion, fighting in the Ukrainian army, rarely provides information regarding casualties and does not release any information about the composition of its volunteer unit.
The Russian air force also bombed positions of the Ukrainian armed forces near Zaytsev, in Donetsk, according to ministry spokesman Igor Konashenkov.
Missile strikes inflicted heavy losses on an artillery division near the southern city of Mykolayiv, he said, although Ukrainian officials said they had only hit infrastructure sites.
Overall, the reports said Russian forces hit eight Ukrainian command points in Donetsk and Mykolaiv, and also destroyed several ammunition arsenals in Donetsk.
The information could not be independently verified.
with DPA
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