Two of the overnight strikes hit tents in the southern city of Khan Younis, each killing two children and their parents.
Other strikes killed a child and a man riding a bicycle, according to Nasser Hospital, which received the bodies from all the strikes.
The Israeli military says it only targets militants and tries to avoid harming civilians.
It blames Hamas for civilian deaths in the 19-month-old war because the militants are embedded in densely populated areas.
There was no immediate Israeli comment on the latest strikes.
Israel has sealed Gaza off from all imports, including food, medicine and emergency shelter, for more than 10 weeks in what it says is a pressure tactic aimed at forcing Hamas to release hostages.
Israel resumed its offensive in March, shattering a ceasefire that had facilitated the release of more than 30 hostages.
Aid groups say food supplies are running low and hunger is widespread.
US President Donald Trump, whose administration has voiced full support for Israel's actions, is set to visit Saudi Arabia, Qatar and the United Arab Emirates this week in a regional tour that will not include Israel.
The war began when Hamas-led militants attacked southern Israel on October 7, 2023, killing some 1200 people, mostly civilians, and taking 251 hostage.
Fifty-nine hostages are still inside Gaza, about a third of them believed to be alive, after most of the rest were released in ceasefire agreements or other deals.
Israel's offensive has killed more than 52,000 Palestinians, mostly women and children, according to Gaza's Health Ministry, which does not say how many of the dead were combatants or civilians.
The offensive has destroyed vast areas of the territory and displaced some 90 per cent of its population of about two million.
In a separate development, Israel said it retrieved the remains of a soldier killed in a 1982 battle in southern Lebanon after he had been classified as missing for more than four decades.
The recovery of Sgt 1st Class Tzvi Feldman's remains brought more closure to a case that has plagued Israel for years.
The Israeli military said his remains were recovered from deep inside Syria, without providing further details.
Feldman went missing, along with five other Israeli soldiers, in a battle with Syrian forces in the Lebanese town of Sultan Yaaqoub.
Several years later, two of the missing soldiers were returned alive to Israel in prisoner exchanges with Syria.
The remains of another soldier were returned in 2019, after Russia said it had helped locate them in Syria, while the fate of the other two remained unknown.
"For many long years, I have authorised numerous covert operations to locate the missing from Sultan Yaaqoub, and I promised the Feldman family that I would never stop working to bring their son home," Israeli Prime Minister Benjamin Netanyahu said on Sunday.
Cases of soldiers missing for decades have a powerful emotional and political resonance in Israel, where military service is compulsory for most Jewish men.
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