Teenager Annabel Sutherland is the shock call-up to Australia's Twenty20 women's World Cup title defence, with Sophie Molineux also back in the squad.
Sutherland was on Thursday confirmed as a member of Australia's 15-woman squad, led by Meg Lanning for next month's tournament.
Veteran Elyse Villani has also been overlooked, falling just short of her bid to reclaim her spot after being dropped after the Ashes last year.
Ellyse Perry is fit after beating a shoulder injury to return for Victoria last week, with 13 of Australia's squad from their win in 2018 still intact.
Allrounder Erin Burns is the other new face alongside Sutherland from outside that title-winning group, although she made her debut late last year.
That leaves Sutherland as the only rookie, who's likely to act as a reserve as pace-bowling allrounder after forcing her way into the squad during a recent A-series.
The daughter of former Cricket Australia boss James Sutherland is seen as a future star after pushing her cause in a recent A-series.
"We're really pleased for Annabel Sutherland, who has been playing domestic cricket for a few years now, as well as being a part of Australia A and under 19 sides," chief selector Shawn Flegler said.
"She has progressed significantly over the past few months.
"Anyone who has seen her play will know how special a talent she is and we know that if called upon she'll be able to play a variety of roles in the side.
"This will be another terrific experience for someone who we see as the future of Australian Cricket."
The squad came together in Melbourne on Wednesday night and have a tri-series with India and England at the end of the month.
Their tournament then begins against India in Sydney on February 21.
Molineux, meanwhile, made her return to cricket last week for Victoria after taking time out of the game during the Big Bash for personal reasons.
She was Australia's chief finger spinner in the last T20 campaign but has battled a shoulder injury for the past year following surgery and has been in and out of the team.
"It's also really pleasing to welcome Sophie Molineux back into the side, having spent some time out of the game for mental health reasons and getting her shoulder right," Flegler said.
"She is a multi-skilled player that offers us another left-arm spinning option alongside Jess Jonassen.
"Sophie made herself available for both tours and we'll continue to manage her health as we go along. Her health is our number one priority."
Molly Strano, Heather Graham and Belinda Vakarewa are among the players who could consider themselves unlucky, having been in the mix in recent months.
AUSTRALIA: Meg Lanning (capt), Rachael Haynes, Erin Burns, Nicola Carey, Ashleigh Gardner, Alyssa Healy, Jess Jonassen, Delissa Kimmince, Sophie Molineux, Beth Mooney, Ellyse Perry, Megan Schutt, Annabel Sutherland, Tayla Vlaeminck, Georgia Wareham.