Police are appealing for public assistance to help locate Warner Clark.
The 42-year-old was last seen in Cobram on Wednesday about 9am.
Police and family have concerns for his welfare as he requires medication.
Warner is 168cm tall, thin build, dark hair and has a beard.
He was last seen wearing a black leather jacket, blue jeans, runners, peak cap and sunglasses.
Police have released an image of Warner in the hope that someone recognises him.
Anyone who sights him or who knows of his whereabouts is urged to contact Cobram Police Station on 5871 1977.